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Microtherapy in Low Back Pain

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  • Create Date March 25, 2008

Experimental in vivo stimulation of the annulus fibrosus of an intervertebral disc produced back pain, and the term “discogenic pain” was coined to establish the association between annulus stimulation and the subjective pain perception. Histologically the end organ neural sensors are located in the outer layers of the annulus, epiannular surface, and the juxta endplate region. Nucleus pulposus and its metabolic byproducts are known contact irritants to the nerve tissues and are known to reduce their membrane excitation threshold. There is no direct contact between the neural end sensors and the intradiscal irritants in an intact disc.

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